Mucoadhesive microparticles as potential carriers in inhalation delivery of doxycycline hyclate: a comparative study
نویسندگان
چکیده
منابع مشابه
Formulation optimization and characterization of spray dried microparticles for inhalation delivery of doxycycline hyclate.
The local delivery of antibiotics in the treatment of infectious respiratory diseases is an attractive alternative to deliver high concentration of antimicrobials directly to the lungs and minimize systemic side effects. In this study, inhalable microparticles containing doxycycline hyclate, sodium carboxymethylcellulose, leucine and lactose were prepared by spray drying of aqueous ethanol form...
متن کاملMucoadhesive Microspheres as carriers in Drug Delivery: a Review
Microspheres constitute an important part of novel drug delivery system by virtue of their small size and efficient carrier capacity. Due to their short residence time, bioadhesive characteristics can be coupled to microspheres to develop mucoadhesive microspheres. Bioadhesion can be defined as the state in which two materials, at least one of which is biological in nature, are held together fo...
متن کاملMucoadhesive Microparticles Engineered for Ophthalmic Drug Delivery.
Although topical drug delivery is a convenient route of administration to treat various eye diseases, it has serious limitations due to rapid clearance of the formulation from the surface of the eye. In this study, we engineered microparticles for both sustained drug delivery and prolonged residence time on the extraocular surface. Microparticles were fabricated by emulsification using poly(lac...
متن کاملa comparative study of the relationship between self-, peer-, and teacher-assessments in productive skills
تمایل به ارزیابی جایگزین و تعویض آن با آزمون سنتی مداد و کاغذ در سالهای اخیر افزایش یافته است. اکثر زبان آموزان در کلاس های زبان از نمره نهایی که استاد تعیین میکند ناراضی اند. این تحقیق جهت بررسی ارزیابی در کلاس های زبان انگلیسی به هدف رضایتمندی زبان آموزان از نمره هایشان انجام گرفته است که در آن نمرات ارائه شده توسط سه گروه ارزیاب (ارزیابی خود دانشجو، همسالان واستاد) در مهارت های تولید (تکل...
15 صفحه اولA comparative study of a range of polymeric microspheres as potential carriers for the inhalation of proteins.
The aim of this study was to compare protein-loaded inhalable microparticles manufactured using a range of biocompatible polymers including hydroxypropyl cellulose (HPC), chitosan, hyaluronic acid, alginate, gelatin, ovalbumin and poly(lactide-co-glycolide) (PLGA). Spray-drying was used to prepare microparticles containing bovine serum albumin labeled with fluorescein isothiocyanate (BSA-FITC)....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Pharmaceutica Sinica B
سال: 2012
ISSN: 2211-3835
DOI: 10.1016/j.apsb.2012.05.001